Research advances on the application of platelet concentrate products in wound repair
10.3760/cma.j.cn501120-20200730-00363
- VernacularTitle:血小板浓缩制品在创面修复中的应用研究进展
- Author:
Yulin LI
1
;
Nuo CHEN
;
Weiguo XIE
Author Information
1. 武汉大学同仁医院暨武汉市第三医院烧伤研究所 430060
- Keywords:
Wound healing;
Platelet-rich plasma;
Biocompatible materials;
Platelet-rich fibrin;
Concentrated growth factor
- From:
Chinese Journal of Burns
2021;37(10):990-995
- CountryChina
- Language:Chinese
-
Abstract:
Multiple growth factors are required to regulate the wound repair process. Currently, there is still a lack of potent, durable, and inexpensive growth factor product in clinical practice. Meanwhile, platelet concentrate products provide an economical, convenient, and effective choice for the treatment of wounds in clinical practice. Starting from the first generation of platelet concentrate products, platelet-rich plasma, researchers have focused on optimizing the performance of platelet concentrate products for higher stability, more abundant bioactive factors, and more optimal clinical performance. Platelet-rich fibrin and concentrated growth factor emerged since then. Platelet concentrate products have the effect of promoting the speed of wound healing and enhancing the quality. This article aims to summarize the history and classification of platelet concentrate products, compare their properties and clinical applications, elaborate their mechanism of action, and analyze the problems existing in relevant researches while prospecting the future development of this field.
