Progress in research of the risk factors of lymph node metastasis in T1 stage colorectal cancer
10.16139/j.1007-9610.2024.04.14
- VernacularTitle:T1期结肠直肠癌淋巴结转移相关危险因素的研究进展
- Author:
Fangqian CHEN
1
;
Wenqing FENG
;
Jingkun ZHAO
;
Yaping ZONG
;
Aiguo LU
Author Information
1. 上海交通大学医学院附属瑞金医院普外科,上海 200025
- Keywords:
Colorectal cancer;
Lymph node metastasis;
Tumor microenvironment;
Transcriptome;
Genome;
Multimodal model
- From:
Journal of Surgery Concepts & Practice
2024;29(4):358-364
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer is one of the common malignant tumors of the digestive tract.With the popularization of screening methods and advancement of endoscopic technology,an increasing number of T1 stage colorectal cancers can be discovered.Accurately predicting lymph node metastasis risk is significantly important for guiding clinical treatment decisions,reducing complications and mortality.Current research on risk factors for lymph node metastasis in T1 stage colorectal cancer covers multiple aspects including clinical pathological features,molecular phenotypes and genetic characteristics.Some studies have built prediction models by integrating these factors,which show higher sensitivity,specificity and accuracy compared to current clinical guidelines.These models provide valuable experience for clinical practice.
