Research advances on skin sweat gland regeneration induced by stem cells and tissue engineering
10.3760/cma.j.cn501120-20200624-00328
- VernacularTitle:干细胞及组织工程诱导皮肤汗腺再生的研究进展
- Author:
Yingnan ZENG
1
;
Yangbo KANG
;
Yong'an XU
Author Information
1. 浙江大学医学院附属第二医院急诊医学科，杭州 310009
- Keywords:
Sweat glands;
Translational research;
Mesenchymal stem cells;
Tissue engineering
- From:
Chinese Journal of Burns
2021;37(9):900-904
- CountryChina
- Language:Chinese
-
Abstract:
As the largest organ in mammals, skin is the first protective barrier against external stimuli. Sweat glands are one of the important cutaneous appendages and play an important role in maintaining electrolyte balance and regulating body temperature. Patients with extensive deep burns usually suffer from damage to deep dermis or the entire skin layer. The damaged sweat glands are difficult to repair and even unable to regenerate, which seriously affects patients' sweating and thermo-regulation function, reduces patients' quality of lives. How to achieve the functionalization of sweat glands has become one of the important researches in regenerative medicine of damaged skin. This review summarizes the translational and application technology of sweat gland regeneration and repair using stem cells and tissue engineering, in order to provide a theoretical basis for the research of sweat gland regeneration.
