Clinical application and mechanism of botulinum toxin type A in scar treatment
10.3760/cma.j.cn501120-20210701-00232
- VernacularTitle:A型肉毒毒素在瘢痕治疗中的临床应用及机制探讨
- Author:
Yixin ZHANG
1
;
Shunuo ZHANG
Author Information
1. 上海交通大学医学院附属第九人民医院整复外科 200011
- Keywords:
Cicatrix;
Botulinum toxins, type A;
Local injection treatment
- From:
Chinese Journal of Burns
2021;37(8):705-710
- CountryChina
- Language:Chinese
-
Abstract:
Pathological scars cause both local physical discomforts and mental disorders for patients. With the development of research, botulinum toxin type A (BTX-A) has been gradually used in the clinical treatment of scars. This article summarizes three potential mechanisms of BTX-A, including early tension reduction, inhibition of connective tissue hyperplasia, and alleviation of skin inflammation, as well as the clinical application of BTX-A in treating different types of scars. However, at present there is no uniform standard for the time, method, and proportioning of BTX-A injection for scar treatment, and there is also a lack of long-term follow-up results. Further researches are needed in future to clarify the mechanism of BTX-A in inhibiting scars, establish a uniform protocol of BTX-A injection, and provide a more effective treatment plan for scars.
