Research advances on the effect of mechanical tension in post-traumatic hypertrophic scar formation
10.3760/cma.j.cn501120-20200315-00167
- VernacularTitle:机械张力对创伤后增生性瘢痕形成的影响研究进展
- Author:
Qiannan ZHAO
1
;
Yuemin ZHOU
;
Chaoyang SUN
Author Information
1. 河南大学淮河医院整形修复外科，开封 475000
- Keywords:
Wounds and injuries;
Cicatrix;
Mechanical tension;
Tension reduction surgery;
Adjuvant intervention
- From:
Chinese Journal of Burns
2021;37(6):586-590
- CountryChina
- Language:Chinese
-
Abstract:
Traumatic scar can not only exert influence on appearance and function of patients, but also affect psychological health status and life quality of patients to varying degrees. At present, scholars have confirmed from basic research that mechanical tension promotes the proliferation of inflammatory cells, fibroblasts, and other cells, as well as angiogenesis and epithelialization through a variety of mechanical conduction pathways and plays an important role in the formation of hypertrophic scar. Clinical studies have confirmed that surgical methods and adjuvant treatment to reduce the mechanical tension on wound can promote wound healing and inhibit hyperplasia of scar. This article summarizes the mechanism of hypertrophic scar formation, and surgical methods and adjunct means of reducing mechanical tension in traumatic wounds, aiming to provide a reference for reducing formation of hypertrophic scar in clinics.
