Research advances on platelet-rich blood products combined with biological materials in wound repair
10.3760/cma.j.cn501120-20200531-00291
- VernacularTitle:富血小板血液制品联合生物材料在创面修复中的应用研究进展
- Author:
Lubing LIU
1
;
Huicai WEN
;
Jinjun HUANG
;
Guizhen XU
;
Huaiwei LIAO
Author Information
1. 南昌大学第一附属医院整形美容科 330006
- Keywords:
Wound healing;
Platelet-rich plasma;
Biocompatible materials;
Regenerative medicine
- From:
Chinese Journal of Burns
2021;37(4):395-400
- CountryChina
- Language:Chinese
-
Abstract:
The efficient management of wounds is the focus of current research. In addition to conventional wound management and necessary surgery, the role of pro-healing drugs in wound treatment has gradually been emphasized. Platelet-rich blood products that is rich in a variety of biologically active molecules are considered as a low-cost and safe therapy in promoting tissue healing, and have great development prospects in the field of regenerative medicine. However, due to the lack of standard preparation and management and the unstable activities of the biomolecules in them, the therapeutic effects of platelet-rich blood products are uneven. In order to solve these problems, researches related to the protection and delivery of biologically active molecules in platelet-rich blood products by biomaterials have gradually increased in recent years, which is also one of the latest trends in wound treatment research. This article first briefly introduces the types of platelet-rich blood products, then outlines the latest research progress achieved by their combination with biomaterials, and finally summarizes the research progress and future research directions of the combination approach in wound treatment.
