Pylorus-preserving Pancreaticoduodenectomy in Pancreatic and Periampullary Carcinomas(Report of 47 Cases).

VernacularTitle:保留幽门的胰十二指肠切除术治疗壶腹周围癌47例报告
From: Journal of Surgery Concepts & Practice 2001;6(2):76-78
CountryChina
Language:Chinese
Abstract: To evaluate the results of pylorus-preservingpancreaticoduodenectomy(PPPD) in the treatment of selected patients with carcinoma of the head of pancreas or of the periampullary region. Methods: From Dec 1984 to Dec 1999, 174 patients with carcinoma of the head of pancreas or of the periampullary region underwent either PPPD(n=47) or standard pancreaticoduodenectomy (PD, n=127); short- and long-term results were compared between the two groups. Results: The incidence of post-operative complications was 34.0% in the PPPD group and 27.6% in the PD group, and the rate of delayed gastric emptying as 8.5% and 6.8%, respectively. There were no significant differences in actuarial survival curves between PPPD and PD, the 5-year survival rate was 47.3% after PPPD and 41.4% after PD. But for patients in stages III and IV, the 5-year survival rate was significantly lower as compared to patients of stages I and II. Conclusions: PPPD might be an acceptable alternative to PD in the treatment of cancer of the head of pancreas or of the periampullary region, if the proximal duodenum or peripyloric lymph nodes were not involved.