Progress of Research on Intestinal Flora and its Metabolites in Ulcerative Colitis
10.3969/j.issn.1008-7125.2024.04.005
- VernacularTitle:肠道菌群及其代谢物与溃疡性结肠炎的研究进展
- Author:
Qiuling HUANG
1
;
Qiuyue HE
;
Yan DU
Author Information
1. 昆明医科大学第一附属医院医学检验科 云南省检验医学重点实验室(650032)
- Keywords:
Colitis,Ulcerative;
Intestinal Flora;
Metabolites;
Pathogenesis;
Therapy
- From:
Chinese Journal of Gastroenterology
2024;29(4):248-253
- CountryChina
- Language:Chinese
-
Abstract:
The incidence of ulcerative colitis(UC)is on the rise globally,but its pathogenesis has not yet been clarified.Existing studies suggest that UC is closely related to genetic susceptibility,impaired intestinal epithelial barrier,abnormal immune response,intestinal flora dysbiosis and environmental factors.Intestinal flora has the functions of substance metabolism,nutrient absorption,energy conversion,immune regulation and maintenance of intestinal mucosal barrier,and has been proved to play an important role in UC.This article reviewed the progress of research on intestinal flora and its metabolites in UC,thus providing theoretical basis and new ideas for the diagnosis and treatment of UC.
