Research Progress of Platelet Abnormalities in Inflammatory Bowel Disease
10.3969/j.issn.1008-7125.2024.04.004
- VernacularTitle:炎症性肠病中血小板异常的研究进展
- Author:
Haichen LI
1
;
Zhewei ZHANG
;
Zhengyu REN
;
Yuling CHEN
;
Yingchao LI
Author Information
1. 西安交通大学第一附属医院消化内科(710061)
- Keywords:
Inflammatory Bowel Disease;
Colitis,Ulcerative;
Crohn Disease;
Platelets;
Therapy
- From:
Chinese Journal of Gastroenterology
2024;29(4):242-247
- CountryChina
- Language:Chinese
-
Abstract:
Platelet is the key factor in hemostasis and coagulation,its potential in inflammatory response and immune response has been widely concerned in recent years.A growing number of studies indicate that tissue damage in inflammatory bowel disease is not only the result of dysregulated immune response,but also the active participation of various other cellular systems,and platelet might play an important role in intestinal mucosal inflammation and immunity.This article reviewed the abnormal changes and possible mechanisms of platelet in inflammatory bowel disease,and the prospects of platelet as a specific treatment target for inflammatory bowel disease.