Vaccine-associated Paralytic Poliomyelitis: A Case Report of Flaccid Monoparesis after Oral Polio Vaccine.
10.3346/jkms.2007.22.2.362
- Author:
Sun Jun KIM
1
;
Sung Han KIM
;
Young Mee JEE
;
Jung Soo KIM
Author Information
1. Department of Pediatrics, Chonbuk National University Hospital, 638-18 Keumam-dong, Dukjin-gu, Jeonju, Korea. sunjun@chonbuk.ac.kr
- Publication Type:Case Report
- Keywords:
Poliovirus vaccine, Poliomyelitis
- MeSH:
Poliovirus Vaccine, Oral/*adverse effects;
Poliomyelitis/*chemically induced/diagnosis/rehabilitation;
Paraplegia/*chemically induced/diagnosis/rehabilitation;
Male;
Infant;
Humans
- From:Journal of Korean Medical Science
2007;22(2):362-364
- CountryRepublic of Korea
- Language:English
-
Abstract:
This report describes a case of acute flaccid paralysis after administration of oral polio vaccine (OPV). A 4 month-old male patient with the decreased movement of left lower extremity for 1 month was transferred to the Department of Pediatrics. He received OPV with DTaP at 2 months of age. Flaccid paralysis was detected 4 weeks after OPV immunization. Attempts to isolate Sabin-like viruses in the two stool and CSF samples failed because those specimens were collected more than 2 month after the onset of paralysis. Hypotonic monoparesis (GIV/V), hypotonia and atrophy on the left lower extremity, and ipsilateral claw foot persisted for more than 18 months, while we followed him with rehabilitation therapy. This is the first case of officially approved, recipient vaccine-associated paralytic poliomyelitis in Korea.
