Research advances on the application of fetal dermal mesenchymal stem cells in burn wound treatment
10.3760/cma.j.cn501120-20191015-00404
- VernacularTitle:胎儿真皮间充质干细胞在烧伤创面治疗中的作用研究进展
- Author:
Yi PAN
1
;
Duyin JIANG
Author Information
1. 山东大学第二医院康复医学科，济南 250033
- Keywords:
Burns;
Wound healing;
Fetal dermal mesenchymal stem cells
- From:
Chinese Journal of Burns
2021;37(1):86-89
- CountryChina
- Language:Chinese
-
Abstract:
Fetal dermal mesenchymal stem cells (FDMSCs) are pluripotent stem cells derived from skin tissue of accidentally aborted fetuses of healthy pregnant women who are free of genetic diseases and do not take abortion drug. FDMSCs have exosome secretion activity, high proliferation and self-renewal abilities, low immunogenicity, and advantages of homing to damaged tissue and promoting tissue regeneration. In recent years, studies on basic biological characteristics, capacity of inducing differentiation in vitro, and promotion of skin wound repair provide new direction for the clinical treatment of burn patients in the future. In this review, we summarize the research advances of FDMSCs in promoting burn wound healing.
