Safety and Effectiveness of Chloral Hydrate for Auditory Brainstem Response Tests in Children
10.3969/j.issn.1006-7299.2024.06.010
- VernacularTitle:水合氯醛应用于儿童ABR检测的安全性和有效性研究
- Author:
Xiangling ZHANG
1
;
Xinyi YAO
;
Min LIU
;
Youyou JIN
;
Zhaoli MENG
;
Haotian LIU
;
Yun ZHENG
Author Information
1. 四川大学华西医院耳鼻咽喉-头颈外科(成都 610041)
- Keywords:
Chloral Hydrate;
Auditory brainstem response;
Sedation failure rate
- From:
Journal of Audiology and Speech Pathology
2024;32(6):524-527
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the safety and effectiveness of chloral hydrate in children undergoing ABR tests.Methods From December 2015 to March 2022,5 513 children under the age of 12 were selected for ABR ex-amination in West China Hospital of Sichuan University,who received chloral hydrate sedation(dose of 30 mg/kg).Data on administration method(mixed or direct),sleep deprivation(yes or no),failure performance(such asfailure to sleep,insufficient sedation,superficial sleep),adverse events(vomiting,irritability,etc.)were retrospectively analyzed.Total sedation failure rate,sedation failure rates in different age groups(≤0.5 years,0.5～3 years,3～12 years)and adverse event rate were calculated.Results Among the 5 513 ABR tests,199(3.61％)failed seda-tion.The sedation failure rates in different age groups(≤0.5 years,0.5～3 years,3～12 years)were 3.03％,4.31％and 3.11％,respectively.In the sedation failure tests,insufficient sedation was found in 81.91％of the tests.The incidence of adverse events was 10.55％,with most commonly vomiting.Conclusion The sedation fail-ure rate and the incidence of adverse events of chloral hydrate at 30 mg/kg were relatively low,thus chloral hydrate can be considered safe and effective at this dose.
