Progression on Research Methods of Noise-induced Hearing Loss Mechanism and Drug Treatment
10.3969/j.issn.1006-7299.2024.03.019
- VernacularTitle:噪声性听力损失机制研究方法及药物治疗进展
- Author:
Tao SUN
1
;
Yueqi LI
;
Ke SHI
;
Liang YANG
;
Xiuming YAN
;
Wei QIU
;
Dan GUO
Author Information
1. 河南医学高等专科学校聋病机制医学重点实验室(郑州 451191)
- Keywords:
Noise-induced hearing loss;
Animal models;
Molecular mechanism;
Molecular targets
- From:
Journal of Audiology and Speech Pathology
2024;32(3):283-288
- CountryChina
- Language:Chinese
-
Abstract:
Noise-induced hearing loss(NIHL)is a public health problem that requires immediate attention.Nearly one-third of hearing loss can be attributed to noise exposure.However,the molecular mechanism of NIHL is complex,and there is currently no specific drug available for preventing and treating NIHL.Therefore,it is particu-larly important to establish standardized preclinical research models of NIHL and identify molecular targets for treat-ment so as to carry out the prevention and drug treatment of NIHL effectively.In this article,we summarized the research methods and pharmacological treatment studies on NIHL to provide references for the prevention and treat-ment of NIHL.