Research status and prospect on autologous tissue-engineered skin as permanent graft
10.3760/cma.j.cn501120-20200204-00043
- VernacularTitle:自体组织工程皮肤作为永久性移植物的研究现状及前景
- Author:
Kun KANG
1
;
Yang SHAO
;
Guodong SONG
Author Information
1. 山东大学附属济南市中心医院烧伤整复外科 250013
- Keywords:
Skin, artificial;
Transplants;
Skin tissue engineering;
Cultured epithelial autograft;
Autologous tissue-engineered composite skin
- From:
Chinese Journal of Burns
2020;36(10):971-974
- CountryChina
- Language:Chinese
-
Abstract:
To date, skin substitute that can provide permanent wound closure is still autologous tissue-engineered skin using autologous skin cells as seed cells. The development of cultured epithelial autograft has experienced a long and tortuous process. Autologous tissue-engineered composite skin is closer to autologous split-thickness skin graft in terms of structure, function, and efficacy, which has become a research focus in recent years. Based on the actual status of research on tissue-engineered skin application, this paper reviewed the main research progresses and existing problems, and the prospect of research and development and clinical application of autologous tissue-engineered skin as permanent graft in order to provide a reference for the improvement and application of autologous tissue-engineered skin.
