Predictors of reperfusion arrhythmia after PCI in patients with acute myocardial infarction: a Meta-analysis
10.3760/cma.j.issn.1674-2907.2018.17.013
- VernacularTitle:急性心肌梗死患者PCI治疗发生再灌注心律失常影响因素的Meta分析
- Author:
Xilan ZHAO
1
;
Ming LI
;
Jizhong LIU
;
Xiao LUO
;
Guoli YANG
Author Information
1. 408000,重庆市涪陵中心医院心血管内科
- Keywords:
Meta-analysis;
Myocardial infarction;
Percutaneous coronary intervention;
Reperfusion arrhythmia;
Predictors
- From:
Chinese Journal of Modern Nursing
2018;24(17):2045-2051
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the predictors of reperfusion arrhythmia (RA) after PCI in patients with acute myocardial infarction (AMI) using Meta-analysis, and to provide evidence for clinical diagnosis and treatment of RA.Methods Firstly, the inclusion and exclusion criteria were restricted and the search strategy was planned. The clinical trials that related to emergency PCI treatment in AMI patients and published before 31st December 2016 were included by two researchers in this study by searching PubMed, CINAHL Database, MEDLINE, Web of Science, Cochrane Libraray, CBM, VIP, CNKI and Wanfang Database. After evaluating the quality of the literature, the Review Manager 5.3 software was used for Meta-analysis.Results A total of 10 studies including 13923 participants were enrolled. The Meta-analysis showed that the risk factors for RA after PCI in AMI patients included: smoking (OR=1.73; 95％CI 1.17-2.56;P<0.01), TIMI0 flow grade (OR=2.74; 95％CI 2.15-3.49;P<0.01), inferior MI (OR=4.52; 95％CI 2.47-8.42;P<0.01), right coronary artery infarction (OR=3.19; 95％CI 1.07-9.58;P=0.04), multi-vasculopathy (OR=3.05; 95％CI 1.83-5.09;P<0.01), renal failure (OR=2.81; 95％CI 1.45-5.43;P< 0.01), time from symptom onset to PCI≤6 h (OR=2.41; 95％CI 1.43-4.07;P<0.01), and duration of operation >1 h (OR=4.03; 95％CI 1.60-10.15;P<0.01). The protective factors included hypertension history (OR=0.76; 95％CI 0.63-0.93;P<0.01) and pre-infarction angina (OR=0.20; 95％CI 0.13-0.30;P<0.01). There were no significant differences in age (OR=1.03; 95％CI 0.95-1.11;P=0.48), history of diabetes (OR=1.26; 95％CI 0.29-5.47;P=0.75), and Killip grade>1 (OR=2.22; 95％CI 0.90-5.48;P=0.08).Conclusions The risk factors for RA after PCI in AMI patients include smoking, TIMI0 flow grade, inferior MI, right coronary artery infarction, multi-vasculopathy, renal failure, time from symptom onset to PCI ≤6 h, and duration of operation >1 h. The hypertension history and pre-infarction angina are protective against RA after PCI in AMI patients.
