Research advances on the roles of exosomes derived from vascular endothelial progenitor cells in wound repair
10.3760/cma.j.cn501120-20190702-00290
- VernacularTitle:血管内皮祖细胞源性外泌体在创面修复中的作用研究进展
- Author:
Manchang PAN
1
;
Xiaoying LIN
;
Hong WANG
;
Yufeng CHEN
;
Min LENG
Author Information
1. 昆明医科大学第二附属医院烧伤科 650000
- Keywords:
Exosomes;
Gene expression;
Endothelial progenitor cells;
Wound repair;
Signal pathway
- From:
Chinese Journal of Burns
2020;36(9):883-886
- CountryChina
- Language:Chinese
-
Abstract:
Angiogenesis is the core step of wound repair, and vascular endothelial progenitor cells (EPC) play an extremely important role during wound repair. Recent studies have shown that vascular EPC-derived exosomes (EPC-Exo) can protect vessels, promote the proliferation and migration of vascular endothelial cells, and have anti-inflammatory, anti-oxidant and anti-apoptotic effects on vascular endothelial cells. This article reviews the mechanism of vascular EPC-Exo in angiogenesis and its potential applications in wound repair in recent years.
