Research update of effects of adipose tissue and component transplantation on scar treatment
10.3760/cma.j.cn501120-20200311-00151
- VernacularTitle:脂肪组织及脂肪成分移植在瘢痕治疗中的作用研究进展
- Author:
Jianghong QI
1
;
Yuan CAI
;
Chengliang DENG
Author Information
1. 遵义医科大学附属医院烧伤整形外科 563003
- Keywords:
Cicatrix;
Adipose tissue;
Adipose-derived stem cells;
Nanofat;
Stromal vascular fraction
- From:
Chinese Journal of Burns
2020;36(7):623-626
- CountryChina
- Language:Chinese
-
Abstract:
Scar is a kind of skin fibroproliferative disease characterized by excessive repair of skin tissue and disorganized deposition of extracellular matrix resulting from deep dermal injury caused by burns or trauma. Scar is accompanied by symptoms such as itching and pain, which could lead to appearance damage and psychological disorders, and is one of the common diseases in burns and plastic surgery clinics. Currently, transplantation of adipose tissue and components is considered as one of the most cutting-edge treatments for scar. Adipose components transplantation includes transplantation of nanofat, adipose-derived stem cell matrix gel, stromal vascular fraction, and adipose-derived stem cell. More and more studies showed that adipose tissue and components possess the functions of tissue regeneration, extracellular matrix remodeling, and anti-fibrosis, which could improve the appearance and symptoms of scar by local transplantation. Therefore, this paper reviews the effects of adipose tissue and components transplantation on scar treatment, aiming to provide theoretical reference for adipose treatment of scar.