Comparative study of sequential nutritional support and parenteral nutrition support in clinical intervention of pediatric acute pancreatitis
- VernacularTitle:小儿急性胰腺炎序贯化营养支持与肠外营养支持的疗效比较
- Author:
Wenshan YANG
1
;
Yu SHENG
;
Xiuli CHEN
;
Ji CHEN
Author Information
- Keywords: pancreatitis,acute necrotizing; parenteral nutrition; child; sequential nutritional support; immunologic function
- From: Tianjin Medical Journal 2024;52(10):1061-1065
- CountryChina
- Language:Chinese
- Abstract: Objective To compare and analyze the effectiveness of sequential nutritional support and parenteral nutrition support in clinical intervention of pediatric acute pancreatitis.Methods Data of 102 children with acute pancreatitis were retrospectively collected and divided into the parenteral nutrition group(n=51)and the sequential nutrition group(n=51)based on the type of parenteral nutrition support.Changes in nutritional status,immune function indicators and body rehabilitation indicators were compared before and after intervention between two groups.The humoral immune indexes(IgA,IgG and IgM)were detected by immunonephelometry.The body recovery indexes(abdominal distension relief time,oral feeding recovery time,body temperature recovery time,blood and urine amylase recovery time and hospital stay)were compared between the two groups.Results After intervention,levels of serum albumin,total protein and prealbumin were higher in the study group than those in the control group,while levels of blood amylase and urine amylase were lower than those in the control group(P＜0.05).After intervention,the CD3+,CD4+and CD4+/CD8+indicators were higher in the study group than those in the control group(P＜0.05).After intervention,IgA,IgG and IgM indicators were higher in the study group than those in the control group(P＜0.05).The relief time of abdominal distension,recovery time of oral feeding,recovery time of body temperature,recovery time of blood and urine amylase and hospitalization time were all shorter in the study group than those in the control group(P＜0.05).Conclusion Sequential nutritional support can effectively improve the nutritional status of children with acute pancreatitis,enhance immune function and promote physical recovery compared to parenteral nutrition support.
