Efficacy and safety of simultaneous prostate biopsy combined with PVP in the treatment of elderly,high-risk and suspected prostate cancer patients
- VernacularTitle:同期前列腺穿刺联合PVP对高龄、高危、可疑前列腺癌患者的疗效及安全性
- Author:
Zhihua ZHANG
1
;
Taihao CHANG
;
Fei LUO
;
Yashen WANG
;
Jian LI
Author Information
- Keywords: prostatic neoplasms; prostatic hyperplasia; prostate biopsy; greenlight laser photoselective vaporization of prostate
- From: Tianjin Medical Journal 2024;52(9):959-963
- CountryChina
- Language:Chinese
- Abstract: Objective To investigate the efficacy and safety of simultaneous prostate biopsy combined with greenlight laser photoselective vaporization of prostate(PVP)in the treatment of elderly,high-risk and suspected prostate cancer(PCa)patients.Methods A retrospective analysis was performed on 37 elderly,high-risk and suspected PCa patients in Tianjin union medical center between June 2018 and December 2022.The surgical time,laser time,postoperative bladder irrigation time,catheter retention time and perioperative complications were recorded respectively.Furthermore,the patients were followed up regarding the International Prostate Symptom Score(IPSS score),Quality of Life Score(QoL score),Maximum Urinary Flow Rate(Qmax)and Residual Urine Volume(PVR).Results All patients were treated with the surgery successfully,with a surgical time of 58(42,67)minutes and a laser time of 48(31,57)minutes.There were 1 case(2.7%)of capsule perforation,1 case(2.7%)of transfer to TURP,and no patients required blood transfusion.No patients had TUR syndrome(TURS),severe hematuria,urinary retention secondary surgery,new acute cardiovascular and cerebrovascular events in the perioperative period.Based on postoperative pathology,29 cases(78.4%)were PCa and 8 cases(21.6%)were benign prostatic hyperplasia.The IPSS[5(4,5)],Qol[2(2,3)],Qmax[16(14,18)mL/s],and PVR[30(24,35)mL]of all patients was improved significantly 12 months after the surgery.Besides,the tPSA level[0.05(0.02,0.37)μg/L]of PCa patients was also significantly decreased.Conclusion Simultaneous prostate biopsy combined with PVP can provide clear diagnosis and improve urinary tract obstruction,and is suitable for elderly,high-risk and suspected PCa patients.
