Effects of fish collagen oligopeptide on operative prognosis of patients with emergency complex hand trauma
10.11958/20231943
- VernacularTitle:鱼胶原低聚肽对急诊复杂手外伤手术患者预后的影响
- Author:
Li LI
1
;
Shuming CAO
;
Zhongping YANG
;
Ruomei HU
Author Information
1. 天津市天津医院营养科(邮编 300211)
- Keywords:
collagenases;
prealbumin;
nutritional support;
prognosis;
fish collagen oligopeptide;
hand injury
- From:
Tianjin Medical Journal
2024;52(8):868-871
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of enteral nutrition with fish collagen oligopeptide on operative prognosis of patients with emergency complex hand trauma.Methods A total of 122 patients who suffered from complex hand trauma and were operated in the emergency department were retrospectively analyzed.Patients were given early enteral nutritional support after the operation,and were divided into two groups according to different formulations.The control group(60 patients)was given balance nutrients and whey protein,and the experimental group(62 patients)was given fish collagen oligopeptide on the same enteral nutrition formula.Clinical data were compared between the two groups,including hemoglobin(Hb),lymphocyte count(Lym),neutrophil-lymphocyte ratio(NLR),albumin(ALB),prealbumin(PA),alanine transaminase(ALT),aspartate transaminase(AST),urea nitrogen(BUN),creatinine(Cr),triglyceride(TG),total cholesterol(TC)and low density lipoprotein-C(LDL-C)before and after treatment.The length of hospital stay and the incidence of postoperative infectious complications were compared between the two groups of patients.Results Compared with before treatment,Hb,ALB,liver and kidney function and lipid metabolism indexes of the control group and the experimental group had no significant changes after nutritional treatment,and PA and Lym were significantly increased,and NLR was significantly decreased.After nutritional treatment,compared with the control group,NLR was decreased more significantly in the experimental group(P<0.01).The incidence of infectious complications was lower in the experimental group than that in the control group,and the length of hospitalization was significantly shortened(P<0.05).Conclusion Early enteral nutrition supplemented with fish collagen oligopeptide in patients with emergency complex hand trauma can promote prealbumin synthesis,reduce the incidence of inflammation and wound infection,and shorten hospital stay.
