Advances in the research of peripheral blood mononuclear cell-derived multipotential cell
10.3760/cma.j.issn.1009-2587.2016.12.013
- VernacularTitle:外周血单个核细胞来源的多潜能细胞的研究进展
- Author:
Ying XIE
1
;
Bin CHEN
;
Hong WANG
;
Kuan WANG
;
Ran LI
Author Information
1. 云南省烧伤研究所
- Keywords:
Cell differentiation;
Mononuclear cell-derived multipotential cells;
Cell therapy;
Tissue regeneration
- From:
Chinese Journal of Burns
2016;32(12):762-764
- CountryChina
- Language:Chinese
-
Abstract:
Mononuclear cell-derived multipotential cell (MOMC) is a unique cell population that derived from circulating CD14+ mononuclear cell,with phenotypic characteristics of CD14+,CD45+,CD34+,as well as type Ⅰ collagen.It can be induced to differentiate into a wide range of mesenchymal lineages,including endothelium-like cells,myocardium-like cells,neuron-like cells,osteoid cells,chondroid cells,lipoid cells,myoid cells,epidermoid cells,and hepatoid cells.More strikingly,MOMC is easy to be obtained,and it can expand easily in vitro,which can be transplantated autologously without ethical limitations.MOMC is an ideal source of cell therapy for tissue regeneration and wound repair.
