Application of cynanchum corymbosum liquid for radiation skin injury in nasopharyngeal carcinoma
10.3760/cma.j.issn.1674-2907.2018.11.018
- VernacularTitle:畲药刺瓜液在防治鼻咽癌放射性皮肤损伤中的应用
- Author:
Dongying ZHANG
1
;
Lianhe YAN
;
Lingling CHEN
;
Huihong FAN
Author Information
1. 323000,浙江省丽水市人民医院肿瘤放疗科
- Keywords:
Nasopharyngeal neoplasms;
Nursing care;
Cynanchum corymbosum liquid;
Prevention;
Radiation skin injury
- From:
Chinese Journal of Modern Nursing
2018;24(11):1316-1319
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of cynanchum corymbosum liquid for radiation skin injury in nasopharyngeal carcinoma patients. Methods A total of 62 patients with nasopharyngeal carcinoma treated with linear accelerator radiotherapy in the Radiotherapy Department of Lishui People's Hospital of Zhejiang Province from July 2014 to June 2015 were randomly divided into observation group (n=30) and control group (n=32) according to the order of admission. Other 60 patients with nasopharyngeal carcinoma treated with Synergy high energy X-ray radiotherapy from July 2015 to June 2016 were randomly divided into observation group (n=30) and control group (n=30). The patients in control group were given routine skin nursing guidance, the observation group were given cynanchum corymbosum liquid to prevent radiation dermatitis based on the control group methods. The occurrence time, cumulative amount and severity of radiation skin injury were observed in the two groups. Results The incidences of skin injury in the observation group of patients treated with linear accelerator radiotherapy were 18 cases, 20 cases and 3 cases respectively in the Ⅰ, Ⅱ, Ⅲdegrees, which were significantly lower than those in the control group (Z=-2.967, P< 0.01). The average cumulative radiation amount were (46.0±4.0), (66.0±2.0) and (68.0±2.0) Gy respectively, which were all greater than those of the control group (t=9.320, 15.445, 8.921; P< 0.01). The incidences of skin injury in the observation group of patients treated with Synergy high energy X-ray radiotherapy were 28 cases and 2 cases respectively in the Ⅰ, Ⅱdegrees, which were significantly lower than those in the control group (Z=-2.967, P< 0.01). The average cumulative radiation amount were (55.2±2.3) Gy and (64.4±2.3) Gy respectively,which were greater than those of the control group (t=17.614, 2.820; P<0.01). Conclusions The cynanchum corymbosum liquid can effectively prevent radiation skin injury in nasopharyngeal carcinoma patients and guarantee the the successful implementation of radiotherapy.
