The Effect of Bacterial Culture for Stone on the Treatment of Post-Surgical Infection Complication After Flexible Ureteroscopic Lithotomy
10.3870/j.issn.1672-0741.23.09.016
- VernacularTitle:结石细菌培养在控制逆行软性输尿管镜激光碎石术后感染性并发症中的作用
- Author:
Yi ZHANG
1
,
2
;
Luping MA
;
Qinzhang WANG
Author Information
1. 石河子大学第一附属医院泌尿外科,石河子 832003
2. 石河子大学医学院,石河子 832003
- Keywords:
kidney stone;
stone culture;
systemic inflammatory response syndrome;
flexible ureteroscopy;
compli-cations
- From:
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
2024;53(5):653-658
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the risk factors for systemic inflammatory response syndrome(SIRS)induced by flexible ureteroscopic lithotripsy(FURL)and compare the diagnostic value of bacterial culture for stone,midstream urine culture and pelvic urine culture in predicting postoperative infection.Methods Patients who underwent FURL for upper urinary tract stones from November 2021 to May 2023 were retrospectively enrolled.The patients were divided into non-SIRS and SIRS groups.We collected midstream urine one day before surgery and stone and pelvic urine samples during surgery.Multivariate lo-gistic regression analysis was used to identify the risk factors for SIRS induced by FURL.Results Totally,326 patients,11.66％(38/326)developed SIRS,and 4.29％(14/326)had severe sepsis.The percentages of positive bacterial cultures for mid-stream urine,pelvic urine and stone cultures were 16.87％(55/326),10.43％(34/326)and 15.95％(52/326),respectively.In the multivariate logistic regression analysis,stone size(P=0.010),operation time(P=0.030),and stone culture(P＜0.01)were identified as independent risk factors for SIRS induced by FURL.Positive bacterial culture for stone was an independent risk factor for postoperative severe sepsis(P=0.047).E.coli was the most common pathogen cultured from the three sam-ples.Compared with midstream urine and pelvic urine,a greater proportion of E.coli in stone were resistant to aminoglycoside and β-lactamase antibiotics.Conclusion Positive bacterial culture for stone was associated with an increased incidence of post-operative SIRS.Bacterial culture for stone might have important clinical value in the treatment of postoperative infection in FURL patients.
