Analysis of Survival Time of HIV Infectors/AIDS Patients in Wuhan from 1994-2022 and the Influencing Factors
10.3870/j.issn.1672-0741.24.05.015
- VernacularTitle:武汉市1994～2022年HIV感染者/AIDS患者的生存时间及其影响因素
- Author:
Nianhua XIE
1
;
Han YAN
;
Hongfei MA
Author Information
1. 武汉市疾病预防控制中心,武汉 430024
- Keywords:
HIV/AIDS;
survival analysis;
influence factor
- From:
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
2024;53(5):641-646
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the survival time and influencing factors of HIV Infectors/AIDS patients in Wuhan from 1994-2022 and provide evidence for future prevention and control strategies.Methods Data on HIV/AIDS epidemiology and antiviral treatment were collected from 1994 to 2022 by the national HIV/AIDS Comprehensive Prevention and Control Data In-formation System.The life table method and Cox proportional hazard regression model were used to analyze survival time and its influencing factors.Results A total of 8954 patients with HIV/AIDS were followed up for 47245.4 person-years,with 1078 deaths from all causes,and the median survival time was 22.3 years.The survival rates at 1,5,10,15,and 20 years were 92.9％,88.5％,83.5％,78.7％,and 73.8％,respectively.The results of the Cox proportional hazard regression model analysis revealed that untreated,older age,unemployed,male,low literacy,native,heterosexual and injection drug transmission,being founcl by medical institution examination,and lower CD4 baseline levels were risk factors for HIV/AIDS patient survival time(untreated vs.treated,HR=13.979,95％CI:11.883-16.446;without stable occupations vs.stable occupations:HR=1.140,95％CI:1.004-1.295;locally registered residence vs.mobile patients:HR=1.682,95％CI:1.415-2.000;medical institution testing findings vs.VCT:HR=1.823,95％CI:1.421-2.339).Conclusion For risk factors such as being 50 years old and a-bove,being unemployed,having a low level of literacy,being detected by medical institutions and having a low CD4 baseline lev-el,we should improve the public's scientific understanding of HIV/AIDS through publicity and education and promote early de-tection and treatment through medical and prevention cooperation and social organization participation.Making full use of healthy big data of HIV/AIDS patients,forming multi-dimensional full-life cycle health files,providing accurate medical care for different individuals,including psychological intervention,and extending life time and improving quality of life are directions for future efforts.
