Research Progress on Photodynamic Therapy in the Treatment of Oral Leukoplakia
10.3870/j.issn.1672-0741.23.01.010
- VernacularTitle:光动力疗法治疗口腔白斑的研究进展
- Author:
Ruoyan ZHANG
1
;
Jun WANG
Author Information
1. 南昌大学第二临床医学院,南昌 330006
- Keywords:
photodynamic therapy;
oral leukoplakia;
photosensitizer;
CO2 laser;
plum-blossom needle
- From:
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
2024;53(3):420-425
- CountryChina
- Language:Chinese
-
Abstract:
Oral leukoplakia(OLK)is defined as the white lesions that occur on the oral mucosa which cannot be erased and cannot be clinically or pathologically diagnosed as any other definable diseases.It is a precancerous lesion of the oral muco-sa.Existing treatments for OLK include non-surgical treatments and surgical treatments.However,promising evidence regard-ing the prevention of malignant transformation and recurrence of OLK by non-surgical treatments(such as pharmacotherapy)is needed.Meanwhile,surgical treatments have limited indications and postoperative oral morphology and function impair-ment.Photodynamic therapy(PDT)is a modern non-invasive therapy,which can be used to treat tumors and non-tumor lesions including oral leukoplakia,and has become a new and promising option for the treatment of oral leukoplakia due to its potential of preserving tissue morphology and function.In this paper,photosensitizers and lights of PDT and adjuvant treatment methods for PDT in the treatment of oral leukoplakia were reviewed.
