A case of nephrotic syndrome in a patient with scleroderma.
- Author:
Il KIM
1
;
Woong HUH
;
Cheol Ku PARK
;
Taey Up CHUNG
;
Shin CHOI
;
Seong Hoon HAN
;
Won Do PARK
Author Information
1. Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea. kimein@freechal.com
- Publication Type:Case Report
- Keywords:
Scleroderma;
Systemic;
Nephrotic syndrome;
Glomerulonephritis
- MeSH:
Biopsy;
Blood Vessels;
Connective Tissue;
Fibrosis;
Glomerulonephritis;
Heart;
Humans;
Hypertension;
Kidney;
Lung;
Necrosis;
Nephrotic Syndrome*;
Pathology;
Proteinuria;
Sclerosis;
Skin
- From:Korean Journal of Medicine
2003;64(1):91-95
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Scleroderma is a connective tissue disorder characterized by fibrosis of the skin, vessels and internal organs (gastrointestinal tract, lung, heart, and kidney etc.). Renal involvement in scleroderma has a clinical manifestation from subnephrotic proteinuria to renal crisis accompanied by hypertension, and shows a typical histology of intimal proliferation and fibrinoid necrosis of blood vessel without primary glomerular pathology. We experienced a case of nephrotic syndrome in a 31-old-female patient with sclerodema. But the patient has not showed a clinical feuture of hypertension or renal crisis, moreover, renal biopsy of the patient showed global sclerosis and crescent formation in the glomeruli without vessel involvement. We report this case with a brief review of literature.
