A case of relapsed renal plasmacytoma after complete remission of multiple myeloma.
- Author:
Su Hong KIM
1
;
Eun Seok KIM
;
Jin Wuk HUR
;
Jae Hwa LEE
;
Seong Hoon CHANG
;
Yang Soo KIM
;
Wan Kyu EO
Author Information
1. Department of Internal Medicine, Kosin University Gospel Hospital, Busan, Korea. dhugie@kosin.md
- Publication Type:Case Report
- Keywords:
Renal plasmacytoma;
Multiple myeloma
- MeSH:
Adult;
Diagnosis;
Drug Therapy;
Eosinophils;
Female;
Fluorescent Antibody Technique;
Humans;
Immune Sera;
Multiple Myeloma*;
Paraproteinemias;
Plasma Cells;
Plasmacytoma*
- From:Korean Journal of Medicine
2003;64(1):114-118
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Extramedullary plasmacytoma is a rare presentation of plasma cell dyscrasia. Most such tumors arise on the upper aerodigestive tract and renal plasmacytoma is very rare. The patient was 44 years old female presented with a 3 month-history of palpable mass in the right flank. There was a past history of complete remission after a chemotherapy for multiple myeloma (6 cycles of VAD chemotherapy) for the two years following the first diagnosis. After surgical resection, histologic and immunofluorescence studies of resected specimens revealed that the renal parenchyma was destroyed by sheets of mature plasma cells producing monoclonal protein (IgG-lambda) and by deposits of amorphous eosinophilic substance stained with anti-lambda antisera. Treatment with chemotherapy of Hyper-CVAD and local irradiation was done. The patient has been disease-free for 3 months after treatment. We report a case of relapsed renal plasmacytoma after complete remission of multiple myeloma.
