Application of zinc agents in Wilson's disease
10.3760/cma.j.cn501113-20231116-00197
- VernacularTitle:锌剂在威尔逊氏病中的应用
- Author:
Chen LIANG
1
;
Wei HOU
;
Zhongping DUAN
;
Sujun ZHENG
Author Information
1. 首都医科大学附属北京佑安医院肝病中心一科,北京 100069
- Keywords:
Wilson disease;
Hepatolenticular degeneration;
Chelating agent;
Therapeutic;
Zinc agent
- From:
Chinese Journal of Hepatology
2024;32(9):850-853
- CountryChina
- Language:Chinese
-
Abstract:
Wilson's disease (WD) is a kind of inherited metabolic liver disease in which most patients need lifelong medication to maintain copper homeostasis in the body. Zinc is one of the most commonly used drugs for WD treatment. However, there are currently few high-quality, large-sample, and prospective clinical trials on zinc agent-treated WD. The selection and application of zinc agents are mainly based on patients' clinical phenotype, tolerance to zinc agents, and physicians' experience in treating WD. This article summarizes the application of zinc agents in WD.