Epidemiological analysis of the current prevalence of hepatitis B virus infection among pregnant and postpartum women in China from 2021 to 2023
10.3760/cma.j.cn501113-20240422-00219
- VernacularTitle:2021-2023年中国孕产妇乙型肝炎病毒现症感染的流行病学分析
- Author:
Dongxu HUANG
1
;
Xiaoyan WANG
;
Qian WANG
;
Ya GAO
;
Yu WANG
;
Changhe WANG
;
Ailing WANG
Author Information
1. 中国疾病预防控制中心妇幼保健中心孕产保健部,北京 100081
- Keywords:
Gravida;
Parturient;
Hepatitis B;
Hepatitis B virus;
Infection;
Epidemiology;
Serology
- From:
Chinese Journal of Hepatology
2024;32(5):449-452
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze hepatitis B serologic tests and the current prevalence of hepatitis B virus (HBV) infection among pregnant and postpartum women in China from 2021 to 2023.Methods:Data on managing the prevention of mother-to-child transmission of HIV, syphilis, and hepatitis were retrieved from the National Information System. A positive serum HBsAg test was used to define HBV infection. The χ2 test was used to compare the coverage rate of the hepatitis B serologic test across different years, in early-stage pregnancy, and the current HBV infection in pregnant and postpartum women. A two-sided P value of <0.05 was considered a statistically significant difference. Results:The coverage rate for hepatitis B serological detection in pregnant (including intrapartum) and postpartum women and early-stage pregnancy rose from 99.68% (10?463?059/10?496?883) and 82.96% (8?707?765/10?496?883) to 99.94% (8?678?777/8?684?387, P ?0.001) and 88.87% (7?717?857/8?684?387, P ?0.001) in China between 2021 and 2023. The current prevalence rate of HBV infection decreased from 4.98% (521?479/10?463?059) in 2021 to 4.56% (396?148/8?678?777) in 2023 among pregnant and postpartum women ( P ?0.001). The current prevalence rate of HBV infection ranged from 1.53% to 10.39% among pregnant and postpartum women in various provinces of China in 2023. Conclusion:The coverage rate for hepatitis B serologic tests in China increased significantly between 2021 and 2023 in pregnant and postpartum women. Therefore, the current prevalence rate of HBV infection has decreased significantly in pregnant and postpartum women, but a regional difference still exists.