Therapeutic strategies, practice, and prospect of a clinical cure for chronic hepatitis B in China
10.3760/cma.j.cn501113-20240325-00156-1
- VernacularTitle:慢性乙型肝炎临床治愈的中国实践、治疗策略和展望
- Author:
Zhishuo MO
1
;
Dongying XIE
;
Bingliang LIN
;
Xiaoguang DOU
;
Mobin WAN
;
Jiaji JIANG
;
Yingren ZHAO
;
Hong TANG
;
Hui ZHUANG
;
Zhiliang GAO
Author Information
1. 中山大学附属第三医院感染科,广州 510630
- Keywords:
Chronic hepatitis B;
Prognosis;
Clinical cure;
Functional cure;
Clinical practice;
Therapeutic strategy;
Interferon;
Nucleos(t)ide analogues
- From:
Chinese Journal of Hepatology
2024;32(5):411-417
- CountryChina
- Language:Chinese
-
Abstract:
Clinical cure (herein referred to as functional cure) is currently recognized as the ideal therapeutic goal by the guidelines for the prevention and treatment of chronic hepatitis B (CHB) at home and abroad. China has achieved significant results in research and exploration based on pegylated interferon alpha therapeutic strategies to promote the effectiveness of CHB clinical cure rates in clinical practice. The summary and optimization of clinical cure strategies in different clinical type classifications, as well as the exploration of clinical cure continuity and long-term outcomes, are of great significance for solving the current bottleneck problem and our future efforts in the developmental directions of clinical cure in CHB populations.