Research progress on pyroptosis in liver diseases
10.3760/cma.j.cn501113-20230115-00030
- VernacularTitle:细胞焦亡在肝脏疾病中的研究进展
- Author:
Rui JIN
1
;
Xiaoxiao WANG
;
Feng LIU
;
Huiying RAO
Author Information
1. 北京大学人民医院 北京大学肝病研究所 丙型肝炎和肝病免疫治疗北京市重点实验室 非酒精性脂肪性肝病诊断北京市国际科技合作基地，北京 100044
- Keywords:
Pyroptosis;
Non-alcoholic fatty liver disease;
Liver diseases
- From:
Chinese Journal of Hepatology
2024;32(3):284-288
- CountryChina
- Language:Chinese
-
Abstract:
Pyroptosis is a newly discovered kind of cell death modality that, due to its association with innate immunity, plays a crucial role in cytolysis and inflammatory cytokine release during host defense against infection. In recent years, studies have shown that pyroptosis plays an important role in the occurrence and development of liver diseases. This article introduces and elaborates on the most recent research progress on pyroptosis in liver diseases based on the morphological features, molecular and pathophysiological mechanisms.
