Prognostic nutritional index application value for acute-on-chronic liver failure co-infection
10.3760/cma.j.cn501113-20240109-00021
- VernacularTitle:预后营养指数对预测慢加急性肝衰竭合并感染的应用价值
- Author:
Yamin WANG
1
;
Yushan LIU
;
Juan LI
;
Qiao ZHANG
;
Taotao YAN
;
Danfeng REN
;
Li ZHU
;
Guoyu ZHANG
;
Yuan YANG
;
Jinfeng LIU
;
Tianyan CHEN
;
Yingren ZHAO
;
Yingli HE
Author Information
1. 西安交通大学第一附属医院感染科，西安 710061
- Keywords:
Liver failure;
Infection;
Prognostic nutritional index
- From:
Chinese Journal of Hepatology
2024;32(3):235-241
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the predictive value of the prognostic nutritional index (PNI) in concurrently infected patients with acute-on-chronic liver failure (ACLF).Methods:220 cases with ACLF diagnosed and treated at the First Affiliated Hospital of Xi'an Jiaotong University from January 2011 to December 2016 were selected. Patients were divided into an infection and non-infection group according to whether they had co-infections during the course of the disease. Clinical data differences were compared between the two groups of patients. Binary logistic regression analysis was used to screen out influencing factors related to co-infection. The receiver operating characteristic curve was used to evaluate the predictive value of PNI for ACLF co-infection. The measurement data between groups were compared using the independent sample t-test and the Mann-Whitney U rank sum test. The enumeration data were analyzed using the Fisher exact probability test or the Pearson χ2 test. The Pearson method was performed for correlation analysis. The independent risk factors for liver failure associated with co-infection were analyzed by multivariate logistic analysis. Results:There were statistically significant differences in ascites, hepatorenal syndrome, PNI score, and albumin between the infection and the non-infection group ( P ?
