Research progress in the effect of Hirsutine on antitumor
10.11904/j.issn.1002-3070.2024.02.009
- VernacularTitle:毛钩藤碱在抗肿瘤作用中的研究进展
- Author:
Dahai YU
1
;
Zhanshi WANG
;
Lizhu ZHAO
Author Information
1. 哈尔滨商业大学药学院(哈尔滨 150078)
- Keywords:
Hirsutine;
Antitumor;
Mechanisms of action;
Pharmacological effects
- From:
Practical Oncology Journal
2024;38(2):136-140
- CountryChina
- Language:Chinese
-
Abstract:
Hirsutine,an indole alkaloid extracted from the traditional Chinese herb Uncaria,has exhibits diverse pharmaco-logical activities,including antihypotensive,antiinfective,and cardioprotection.In cervical cancer,breast cancer,colon cancer,and oth-er malignant tumors,hirsutine has effects on anti-tumor by regulating cell apoptosis,immune regulation and other pathways,laying the foundation for the application of hirsutine in the field of cancer therapy.This article reviews relevant literature both domestically and internationally to elucidate the research progress of hirsutine in anti-tumor therapy,providing new ideas and strategies for cancer treat-ment.
