HVPG minimally invasive era: exploration based on forearm venous approach
10.3760/cma.j.cn501113-20231220-00289
- VernacularTitle:肝静脉压力梯度微创时代：基于前臂静脉入路的探索
- Author:
Jitao WANG
1
;
Lei LI
;
Meng NIU
;
Qingliang ZHU
;
Zhongwei ZHAO
;
Kohei KOTANI
;
Akira YAMAMOTO
;
Haijun ZHANG
;
Shuangxi LI
;
Dan XU
;
Ning KANG
;
Xiaoguo LI
;
Kunpeng ZHANG
;
Jun SUN
;
Fazong WU
;
Hailong ZHANG
;
Dengxiang LIU
;
Muhan LYU
;
Jiansong JI
;
Norifumi KAWADA
;
Ke XU
;
Xiaolong QI
Author Information
1. 河北省肝硬化门静脉高压重点实验室 河北医科大学附属邢台市人民医院 邢台 054000
- Keywords:
Liver cirrhosis;
Hepatic venous pressure gradient;
Forearm vein
- From:
Chinese Journal of Hepatology
2024;32(1):35-39
- CountryChina
- Language:Chinese
-
Abstract:
Objective:The transjugular or transfemoral approach is used as a common method for hepatic venous pressure gradient (HVPG) measurement in current practice. This study aims to confirm the safety and effectiveness of measuring HVPG via the forearm venous approach.Methods:Prospective recruitment was conducted for patients with cirrhosis who underwent HVPG measurement via the forearm venous approach at six hospitals in China and Japan from September 2020 to December 2020. Patients' clinical baseline information and HVPG measurement data were collected. The right median cubital vein or basilic vein approach for all enrolled patients was selected. The HVPG standard process was used to measure pressure. Research data were analyzed using SPSS 22.0 statistical software. Quantitative data were used to represent medians (interquartile ranges), while qualitative data were used to represent frequency and rates. The correlation between two sets of data was analyzed using Pearson correlation analysis.Results:A total of 43 cases were enrolled in this study. Of these, 41 (95.3%) successfully underwent HVPG measurement via the forearm venous approach. None of the patients had any serious complications. The median operation time for HVPG detection via forearm vein was 18.0 minutes (12.3~38.8 minutes). This study confirmed that HVPG was positively closely related to Child-Pugh score ( r = 0.47, P = 0.002), albumin-bilirubin score ( r = 0.37, P = 0.001), Lok index ( r = 0.36, P = 0.02), liver stiffness ( r = 0.58, P = 0.01), and spleen stiffness ( r = 0.77, P = 0.01), while negatively correlated with albumin ( r = -0.42, P = 0.006). Conclusion:The results of this multi-centre retrospective study suggest that HVPG measurement via the forearm venous approach is safe and feasible.
