Comprehensive diagnosis and treatment of a patient presenting with aortic valve vegetations due to Infec-tive endocarditis
10.3969/j.issn.1006-5725.2024.21.024
- VernacularTitle:一例主动脉瓣感染性心内膜炎致瓣膜赘生物患者的综合诊治
- Author:
Peisen HUANG
1
;
Ruicong XUE
;
Jiangui HE
;
Yugang DONG
;
Chen LIU
Author Information
1. 中山大学附属第一医院心内科(广东 广州 510080)
- Keywords:
Q fever infective endocarditis;
aortic valve vegetations;
infective endocarditis;
rickettsia
- From:
The Journal of Practical Medicine
2024;40(21):3113-3118
- CountryChina
- Language:Chinese
-
Abstract:
A 36-year-old male patient was hospitalized due to persistent chest tightness and dyspnea last-ing over 10 days.An echocardiogram revealed significant aortic valve regurgitation,the presence of vegetation on the aortic valve,severe mitral valve regurgitation,and enlargement of both the left atrium and left ventricle.Follow-ing a comprehensive multidisciplinary consultation,the focus was directed towards the aortic valve vegetation as the primary concern,with particular attention given to the potential diagnosis of blood culture-negative infective endocarditis(IE)and non-bacterial thrombotic endocarditis,while differentiating it from rheumatic heart disease.Ultimately,the vegetation was excised during a surgical aortic valve replacement procedure,which facilitated histopathological examination,biological culture,and high-throughput metagenomic sequencing of pathogenic mi-croorganisms.The definitive diagnosis was established as aortic valve infective endocarditis(Q fever IE)leading by infection of Coxiella burnetii.
