Natural history of chronic hepatitis B virus infection under low-level viremia
10.3760/cma.j.cn501113-20220907-00461
- VernacularTitle:自然状态下乙型肝炎病毒慢性感染中的低病毒血症
- Author:
Meimei YAN
1
;
Lihua SUN
Author Information
1. 新疆医科大学第一附属医院感染病肝病中心，乌鲁木齐 830054
- Keywords:
Chronic hepatitis B;
Low level viremia;
Natural state
- From:
Chinese Journal of Hepatology
2023;31(3):322-326
- CountryChina
- Language:Chinese
-
Abstract:
Low-level viremia (LLV) is a hot and difficult topic that has gradually attracted attention in the field of chronic hepatitis B for evaluating antiviral therapy response in recent years. The presence of LLV may increase drug-resistant mutations, the progression of liver fibrosis, and potentially the development of liver cancer following antiviral therapy. Natural history of chronic HBV infection patients also have LLV, but it is unclear whether these patients are also at risk of disease progression, what the risk is, and whether early antiviral therapy is necessary and beneficial. Therefore, this article provides a reference for the all-encompassing management of this group of patients by reviewing the prevalence and impact of LLV in chronically HBV-infected patients' natural histories.
