Quantitative diagnosis of annular pancreas in neonates with saline-contrast ultrasound
10.3969/j.issn.1006-5725.2024.18.019
- VernacularTitle:超声生理盐水造影对新生儿环状胰腺的定量诊断价值
- Author:
Boyang YANG
1
;
Qian FANG
;
Yi ZHENG
;
Hongying WANG
Author Information
1. 广州医科大学附属妇女儿童医疗中心超声科(广州 510623)
- Keywords:
neonate;
annular pancreas;
ultrasound;
dilated duodenum diameter;
dilated duode-num thickness;
stenotic duodenum diameter
- From:
The Journal of Practical Medicine
2024;40(18):2618-2622
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical utility of ultrasound parameters in diagnosing neonatal annular pancreas.Methods A total of 56 neonates with descending duodenal obstruction underwent saline-contrast ultrasound examination.Ultrasonic parameters,including dilated duodenum diameter(DDD),dilated duodenum thickness(DDT),and stenosis duodenum diameter(SDD),were measured.The cases were categorized into three groups:annular pancreas(group A,n=28),descending duodenal atresia(group B,n=3),and descending duodenal septum(group C,n=25).One-way ANOVA was employed to compare statistical differences among the three ultrasonic parameters across the groups,followed by LSD-t test for pairwise comparisons between two groups showing significant differences.Receiver operating characteristics analysis was conducted to calculate the area under the curve and determine the cut-off value if there were statistically significant differences observed.Results In group A,group B,group C,the diameters of DDD were measured as(23.2±2.4)mm,(25±1.0)mm,(19.4±2.6)mm,respectively.When comparing these three groups,there was a statistically significant difference between group A or group B and group C in terms of DDD diameter measurements(t=5.7,P＜0.05;t=3.793,P＜0.05).However,no statistically significant difference was observed between group A and group B for DDD diameter measurements(t=1.232,P＞0.05).The corresponding values for DDT were measured as(3.0±0.6)mm,(3.2±0.4)mm,and(2.4±0.3)mm,respectively.When comparing these three groups,the results showed a statistically significant differ-ence between either Group A or Group B compared to Group C in terms of DDT measurement(t=4.695,P＜0.05;t=2.778,P＜0.05).However,no statistically significant difference was found between Group A and Group B regard-ing the measurement of DDT(t=0.666,P＞0.05).The SDD measurements in the three groups were(1.9±0.3)mm,(3.6±0.8)mm,(5.5±0.7)mm,respectively.Statistical analysis using LSD-t test revealed significant differences between the three groups(t=5.521,P＜0.05;t=6.142,P＜0.05;t=25.828,P＜0.05).The sensitivity,specificity,positive predictive value,and negative predictive value for detecting annular pancreas at a cutoff of 2.3 mm were determined to be 96.4%,100%,100%,and 96.6%,respectively,with an area under the receiver operating charac-teristic curve of 0.999.Conclusion SDD could be employed for the diagnosis of neonatal annular pancreas.
