A case of neurosarcoidosis without systemic involvement.
- Author:
Seung Ho CHOI
1
;
Ji Eun KIM
;
Hyung LEE
;
Jeong Geun LIM
;
Sang Do YI
;
Young Choon PARK
Author Information
1. Department of Neurology, Keimyung University School of Medicine.
- Publication Type:Case Report
- Keywords:
sarcoidosis;
cranial neuropathy;
peripheral polyneuropathy;
noncaseous granulomatous inflammation
- MeSH:
Biopsy;
Cranial Nerve Diseases;
Epithelioid Cells;
Female;
Humans;
Inflammation;
Middle Aged;
Nervous System;
Polyneuropathies;
Sarcoidosis;
Sural Nerve
- From:Journal of the Korean Neurological Association
1998;16(5):728-731
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Sarcoidosis is a multisystem disorder of unknown cause. The involvement of the nervous system occurs 5% to 27% of patients with sarcoidosis, and neurosarcoidosis without systemic involvement is rare and difficult to diagnose. We present a case of 58-year-old woman with clinical features of multiple cranial and peripheral polyneuropathy with noncaseating granulomatous inflammation. Extensive testing for occult systemic sarcoidosis was negative. Sural nerve biopsy showed several perineural noncaseous granulomatous inflammation with prominent epithelioid cells. Oral steroid therapy led to some improvement. We report a patient with multiple cranial and peripheral polyneuropathy without systemic involvement, suspected sarcoidosis.
