Research progress of acetaldehyde dehydrogenase 2 in liver diseases
10.3760/cma.j.cn501113-20201101-00591
- VernacularTitle:乙醛脱氢酶2在肝脏疾病中的研究进展
- Author:
Xingyu YANG
1
;
Jun LUO
;
Boyu CHEN
;
Qiao CHEN
;
Zhongzhong LIU
;
Qifa YE
Author Information
1. 武汉大学中南医院 武汉大学肝胆疾病研究院 武汉大学移植医学中心 移植医学技术湖北省重点实验室，武汉 430071
- Keywords:
Alcoholic liver disease;
Acetaldehyde dehydrogenase 2;
Hepatocellular carcinoma;
Molecular mechanism
- From:
Chinese Journal of Hepatology
2022;30(12):1397-1400
- CountryChina
- Language:Chinese
-
Abstract:
Acetaldehyde dehydrogenase 2 (ALDH2) is an important kind of aldehyde dehydrogenase in mitochondria, which has the function of eliminating acetaldehyde and other toxic aldehydes substances. Furthermore, it is abundant in liver and is closely related to the occurrence and development of a variety of liver diseases. ALDH2 genetic polymorphisms plays an important role in the occurrence of a variety of liver diseases in the human population.This paper mainly reviews the research progress of ALDH2 in liver diseases in recent years, with a view to provide theoretical basis for clinical prevention and treatment.
