Mechanism and research progress of dexmedetomidine in improving perioperative neurocognitive disorder in frail elderly patients
10.3969/j.issn.1006-5725.2024.17.025
- VernacularTitle:右美托咪定改善衰弱老年围术期神经认知障碍的机制及研究进展
- Author:
Zhiyan XU
1
;
Weiyuan CHEN
;
Weifeng YAO
Author Information
1. 梅州市人民医院(广东梅州 514000)
- Keywords:
dexmedetomidine;
frailty;
perioperative neurocognitive disorder
- From:
The Journal of Practical Medicine
2024;40(17):2503-2507
- CountryChina
- Language:Chinese
-
Abstract:
With the acceleration of population aging and the continuous growth of the elderly population,frailty has become a global public health problem.At the same time,an increasing number of elderly people require surgical treatment,and people are paying more attention to the possible postoperative neurocognitive disorder.Frailty and neurocognitive disorder interact with each other,forming a vicious cycle.Improving one of them can improve the prognosis of the elderly.As one of the commonly used anesthetic drugs in clinical practice,dexmedeto-midine has neuroprotective effects.This article reviews the relationship between frailty and neurocognitive disorder,as well as the research progress of dexmedetomidine in improving perioperative neurocognitive disorder in frail elderly patients.
