Factors associated with critical weight loss among cancer patients during proton and heavy ion therapy based on the decision tree model
10.3760/cma.j.issn.1674-2907.2017.33.008
- VernacularTitle:基于决策树模型质子重离子治疗期间肿瘤患者显著体重下降的影响因素分析
- Author:
Zhihong ZHANG
1
;
Yu ZHU
;
Hongwei WAN
;
Ziying WANG
;
Lijuan ZHANG
Author Information
1. 同济大学附属第一妇婴保健院护理部
- Keywords:
Neoplasms;
Proton therapy;
Heavy ion radiotherapy;
Weight loss;
Influencing factor;
Decision tree model
- From:
Chinese Journal of Modern Nursing
2017;23(33):4218-4223
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influencing factors of proton and heavy ion therapy based on decision tree model for significant weight loss among patients with cancer so as to provide research foundation for the implementation of preventive nutritional support. Methods The associated factors of critical weight loss were investigated among 375 cancer patients in Shanghai Proton and Heavy Ion Center from June 2015 to June 2016. Results The mean weight loss was 0.5 kg during proton or heavy ion therapy, with only 11% of the patients lost more than 5% of the weight. Results of univariate analysis indicated that age, tumor site, recurrence or not, concurrent chemotherapy, surgical history, radiotherapy modality, total dose and total fractions were significantly associated with critical weight loss. Results of decision tree showed total fraction was the principal discriminator, the next division was tumor site and radiotherapy modality, and surgical history was the last determinant of critical weight loss. Conclusions Total fractions, tumor site, radiotherapy modality and surgery history were significant factors of critical weight loss during proton and heavy ion therapy, which helps the healthcare staff identify the high risk cancer patients, and offer predictive nutrition support before radiotherapy.
