Research progress on the role of bile acids in alcoholic liver disease
10.3969/j.issn.1006-5725.2024.15.025
- VernacularTitle:胆汁酸在酒精性肝病中的作用研究进展
- Author:
Nan LI
1
;
Xue ZHAO
;
A'nali
;
Heran LIANG
;
Na GE
Author Information
1. 包头医学院 公共卫生学院(内蒙古包头 014040)
- Keywords:
alcoholic liver disease;
bile acid;
intestinal flora;
enterohepatic circulation
- From:
The Journal of Practical Medicine
2024;40(15):2187-2193
- CountryChina
- Language:Chinese
-
Abstract:
Alcoholic liver disease is liver disease caused by heavy and/or chronic alcohol consumption.Bile acids are synthesized in the liver and regulate the body through liver-intestinal circulation.Many studies have shown that bile acid is closely related to alcoholic liver disease.Alcohol intake can cause liver damage by affecting bile acid synthesis,hepato-enteric circulation and intestinal flora.This article summarizes the mechanism of action of bile acids in alcoholic liver disease and the current research status of improving alcoholic liver disease based on bile acid regulation,in order to provide new ideas for future research on the prevention and treatment of alcoholic liver disease.
