Acute Fibrinous and Organizing Pneumonia Following Hematopoietic Stem Cell Transplantation.
10.3904/kjim.2009.24.2.156
- Author:
Sang Min LEE
1
;
Jae Jung PARK
;
Sun Hee SUNG
;
Yookyung KIM
;
Kyoung Eun LEE
;
Yeung Chul MUN
;
Soon Nam LEE
;
Chu Myong SEONG
Author Information
1. Department of Internal Medicine, Inje University College of Medicine, Busan, Korea.
- Publication Type:Case Report
- Keywords:
Acute fibrinous;
organizing pneumonia;
Hematopoietic stem cell transplantation;
Graft-versus-host disease
- MeSH:
Acute Disease;
Anti-Bacterial Agents/therapeutic use;
Biopsy;
Cryptogenic Organizing Pneumonia/etiology/pathology;
Fatal Outcome;
Glucocorticoids/administration & dosage;
Hematopoietic Stem Cell Transplantation/*adverse effects;
Hemoptysis/etiology;
Humans;
Leukemia, Myeloid, Acute/*surgery;
Lung Diseases/*etiology/pathology;
Male;
Middle Aged;
Pleural Effusion/etiology;
Pulse Therapy, Drug;
Radiography, Thoracic;
Respiratory Insufficiency/etiology;
Tomography, X-Ray Computed
- From:The Korean Journal of Internal Medicine
2009;24(2):156-159
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 60-year-old man presented with cough, sputum, and dyspnea. He had a history of acute myeloid leukemia and hematopoietic stem cell transplantation with chronic renal failure. Chest CT scans showed miliary nodules and patchy consolidations. Histological examination revealed numerous fibrin balls within the alveoli and thickening of the alveolar septum, both of which are typical pathological features of acute fibrinous and organizing pneumonia (AFOP). We report the first case of AFOP following allogeneic hematopoietic stem cell transplantation.