Gastrointestinal endoscopy in the diagnosis and treatment of biliary liver disease
10.3760/cma.j.cn501113-20220427-00222
- VernacularTitle:胆源性肝脏疾病消化内镜的诊断与治疗
- Author:
Xueying LIANG
1
;
Huiguo DING
Author Information
1. 首都医科大学附属北京佑安医院肝病消化中心，北京 100069
- Keywords:
Endoscopic ultrasonography;
Biliary related liver disease;
Cholestasis liver diseases;
Endoscopic retrograde cholangiopancreatography;
SpyGlass
- From:
Chinese Journal of Hepatology
2022;30(7):690-695
- CountryChina
- Language:Chinese
-
Abstract:
Biliary liver disease refers to intrahepatic and extrahepatic bile duct system lesions or bile duct epithelial cells damage, resulting in abnormal liver function, inflammation and fibrosis, which mainly manifests as chronic cholestatic liver disease. The common causes include primary biliary cholangitis, primary sclerosing cholangitis, progressive familial intrahepatic cholangitis, bile duct complications after liver transplantation, and vanishing bile duct syndrome caused by drugs or serious infections, and the most prominent symptoms affecting the patients quality life is pruritus and jaundice. Endoscopic retrograde duodenoscopic cholangiopancreatography and cholangiopancreatoscopy (SpyGlass) and other endoscopic examinations can significantly improve the accuracy of early differential diagnosis,cytology and biopsy of primary sclerosing cholangitis, immunoglobulin G4-related cholangitis and cholangiocarcinoma. Endoscopic nasobiliary drainage, balloon dilatation and intrabiliary stent implantation can significantly improve pruritus symptoms, liver biochemical indicators and prognosis. Therefore, gastrointestinal endoscopy has important value and application prospects in the diagnosis and treatment of biliary liver diseases.
