Effects of two medicines for prevention of acute radiation skin injury in radiation field among liver cancer patients with Cyberknife therapy
10.3760/cma.j.issn.1674-2907.2017.29.019
- VernacularTitle:两种药物预防射波刀治疗肝癌患者照射野皮肤急性放射性损伤的效果观察
- Author:
Liying LIU
1
;
Xiaotong ZHAO
;
Hong ZHANG
;
Qianqian ZHANG
;
Baoying QIAO
;
Qianhui YAO
;
Ya'nan ZHANG
;
Yanmin SHANG
Author Information
1. 解放军三〇二医院肿瘤放射治疗中心肝脏肿瘤科
- Keywords:
Liver neoplasms;
Cyberknife;
Radiation damage;
Skin protection
- From:
Chinese Journal of Modern Nursing
2017;23(29):3769-3771
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the protective effect of DWK skin protectant and Sanyrene for prevention of acute radiation skin injury in radiation field among liver cancer patients with Cyberknife therapy. Methods A total of 100 liver cancer patients with Cyberknife therapy were selected by convenience sampling from March to November 2016. They were randomly divided into the group of DWK and the group of Sanyrene with 50 cases in each group. Skins in radiation field on hepatic region of patients in two groups used DWK skin protectant and Sanyrene respectively since one day before radiotherapy. The acute radiation skin injury of radiation field on hepatic region was observed from one day before treatment to two weeks the end of treatment during Cyberknife therapy.Results The scores of The Radiation Induced Skin Reaction Assessment Scale (RISRAS), an instrument for assessing the degree of acute radiation skin injury of radiation field on hepatic region, of patients in two groups increased with the increasing cumulated dose of irradiation with significant differences (F=3.780, 12.325;P<0.05). There were statistically significant differences in evaluations at the fifth and beyond between two groups (t=5.213, 12.437, 16.846;P<0.05).Conclusions Intervention for local prevention can alleviate the acute radiation skin injury in radiation field on hepatic region among liver cancer patients with Cyberknife therapy. The protective effect of DWK skin protectant on skin in radiation field on hepatic region among liver cancer patients with Cyberknife therapy is better than that of Sanyrene.
