Advances in the study of the role of adenosine 2A receptor in liver injury
10.3760/cma.j.cn501113-20191204-00446
- VernacularTitle:腺苷2A受体在肝脏损伤中的作用研究进展
- Author:
Yuli CAI
1
;
Xiaolin CHEN
;
Bo YI
;
Junfeng LI
;
Zhongyuan WEN
;
Yingan JIANG
Author Information
1. 武汉大学人民医院内分泌科,武汉 430060
- Keywords:
Liver;
Adenosine;
Adenosine 2a receptor
- From:
Chinese Journal of Hepatology
2021;29(9):904-907
- CountryChina
- Language:Chinese
-
Abstract:
Adenosine, as an endogenous purine nucleoside, is widely distributed in various tissues and organs of the body. It binds to adenosine receptors to regulate a variety of important biological processes. Adenosine 2A receptors have a close relationship with the occurrence and development of various clinical diseases. This article reviews the research progress of adenosine 2A receptors in non-alcoholic fatty liver disease, acute immune hepatitis, liver ischemia-reperfusion injury, liver fibrosis, etc., in order to provide new research strategies for the prevention and treatment of these diseases.