Risk factor analysis on ventilator associated pneumonia among multiple injury patients with mechanical ventilation in comprehensive ICU
10.3760/cma.j.issn.1674-2907.2017.28.002
- VernacularTitle:综合ICU多发伤机械通气患者VAP危险因素分析
- Author:
Baorong WANG
1
;
Shengqiang ZOU
;
Tiantian ZHOU
Author Information
1. 江苏大学医学院
- Keywords:
Intensive care units;
Pneumonia;
ventilator-associated;
Multiple injury;
Risk factors
- From:
Chinese Journal of Modern Nursing
2017;23(28):3570-3575
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the risk factors of VAP among multiple injury patients in comprehensive ICU so as to provide the basis for prevention and cure of VAP.MethodsThe retrospective analysis was made to the clinical data from 126 patients with mechanical ventilation for over 48 hours in ICU at the Third People's Hospital of Zhenjiang,the Affiliated Hospital of Jiangsu University,from January 2014 to December 2015. The Logistic regression analysis was performed to research related data in order to identify the risk factors of VAP.ResultsIn 126 patients,there were 37 (29.37%) patients with VAP. Single factor analysis showed that the risk factors were the time of mechanical ventilation,score of the injury severity scale (ISS), time of being admitted to ICU,coma,sedation and analgesia,hormone use,medical history of chronic lung disease,combined antibiotic (>2 kinds),craniocerebral trauma,thoracic injury,spinal injury with significant differences (t/χ2=3.382,20.241,4.212,29.837,7.616,5.322,4.384,8.246,5.677,15.394,4.864;P<0.05). Logistic regression analysis revealed that the risk factors of VAP in multiple injury patients were the time of mechanical ventilation,score of ISS,coma,combined antibiotic (>2 kinds),medical history of chronic lung disease,craniocerebral trauma,thoracic injury (OR=3.897,6.697,5.506,5.104,10.984,4.911,6.046;P<0.05). ConclusionsThe incidence of VAP is high among multiple injury patients in comprehensive ICU. The monitor of risk factors of VAP in multiple injury patients should be enhanced. Moreover,the effective intervention on prevention and cure of VAP should be taken for patients with long time of mechanical ventilation,high score of ISS,coma,combined antibiotic (>2 kinds),medical history of chronic lung disease,craniocerebral trauma, thoracic injury and so on so as to reduce the incidence of VAP.