Research progress on non-alcoholic fatty liver disease animal models
10.3760/cma.j.cn501113-20191209-00452
- VernacularTitle:非酒精性脂肪性肝病动物模型研究进展
- Author:
Hongli YANG
1
;
Guide GAO
;
Chuanli LIU
;
Fajuan RUI
;
Zhaoyang GUO
;
Wanhua REN
;
Jie LI
Author Information
1. 山东大学附属省立医院，济南 250021
- Keywords:
Non-alcoholic fatty liver disease;
Animal model;
Hepatitis;
Fibrosis;
Liver cell carcinoma
- From:
Chinese Journal of Hepatology
2021;29(8):812-816
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, with the changes in living standards and dietary structure, the incidence of non-alcoholic fatty liver disease has been increasing year by year in China, and the incidence rate in the general population is as high as 29.81%. An increasingly epidemiological evidence suggests that non-alcoholic fatty liver disease has become one of the causes of increasing liver cirrhosis and liver cancer. However, its etiology and pathogenesis are complex and have not yet been fully elucidated. Therefore, establishing an appropriate non-alcoholic fatty liver disease animal models for pre-clinical research is essential to elucidate its pathogenesis. This article summarizes the latest research progress of non-alcoholic fatty liver disease animal models, which are common at home and abroad in recent years.
