Effect of Er-Chen-Er-Huang diet therapy on the visual acuity and the fundus of the patients with wet age-related macular degeneration
10.3760/cma.j.issn.1674-2907.2017.27.014
- VernacularTitle:二陈二黄食疗方对湿性老年黄斑变性患者视力和眼底的影响
- Author:
Xiangmei SONG
1
;
Qingshan CHEN
;
Xun WANG
;
Guoming ZHANG
;
Dan XU
Author Information
1. 518040,深圳市眼科医院 深圳眼科学重点实验室一病区
- Keywords:
Wet macular degeneration;
Diet therapy;
Intravitreal injection;
Er-Chen-Er-Huang diet therapy;
Visual acuity;
Fundus
- From:
Chinese Journal of Modern Nursing
2017;23(27):3496-3499
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of Er-Chen-Er-Huang diet therapy on the visual acuity and the fundus of the patients with the wet age-related macular degeneration after the intravitreal injection of ranibizumab.Methods Fifty-eight patients (fifty-eight eyes) with the wet age-related macular degeneration (w-AMD) who were treated with the intravitreal injection of ranibizumab from June 2015 to August 2016 were included. They were divided into the control group (n=29) and the observation group (n=29) according to the random number table. The patients in the control group was fed with the normal diet. The patients in the observation group was supplemented with Er-Chen-Er-Huang diet. The ETDRS score, the CRT thickness, and the CNV lesion leakage control of the patients in two groups were observed after the three-month follow-up. Results One month after the treatment, the ETDRS score of the patients in the control group was (34.44±5.04), and the score of the patients in the observation group was (33.60±5.42). There was no significant difference between the two groups (t=1.054,P=0.297). Three months after the treatment, the ETDRS score of the patients in the control group was (39.60±4.41), which was significantly lower compared to the observation group (42.16±3.77)(t=2.207,P=0.032). One month after the treatment, the CRT thickness of the patients inthe control group was (346.36±48.87)μm. The CRT thickness of the patients in the observation group was (340.16±51.08)μm. There was no significant difference between the 2 groups (t=0.439,P=0.663).Three months after the treatment, the CRT thickness of the patients in the control group was (318.96±45.22)μm, which was significantly thicker compared to the observation group (286.28±44.62)μm(t=-2.572,P=0.013). The total effective rate of the CNV lesion leakage control of the patients in the observation group was 88.0%, which was significantly higher compared with 64.0% of the control group (P<0.05).Conclusions The intravitreal injection of ranibizumab combined with the diet therapy has a more obvious and longer effect on the improvement of the patients'visual acuity,the alleviation of the macular oedema and the occlusion of the CNV leakage than the only intravitreal injection of ranibizumab.
