Research progress of hepatic non-parenchymal cells in nonalcoholic steatohepatitis
10.3760/cma.j.cn501113-20200301-00080
- VernacularTitle:非肝实质细胞在非酒精性脂肪性肝炎中的研究进展
- Author:
Tianxiang ZHENG
1
;
Rong LI
;
Peng TAN
;
Meizhou HUANG
;
Baolin QIAN
;
Hao CHEN
;
Wenguang FU
Author Information
1. 西南医科大学附属医院肝胆外科，泸州 646000
- Keywords:
Nonalcoholic steatohepatitis;
Nonparenchymal cells;
Liver sinusoidal endothelial cells;
Kupffer cells;
Hepatic stellate cells;
Pathogenesis
- From:
Chinese Journal of Hepatology
2021;29(7):711-715
- CountryChina
- Language:Chinese
-
Abstract:
Non-alcoholic steatohepatitis (NASH) is an important link for the progression of metabolic-related fatty liver disease to end-stage liver disease such as cirrhosis and hepatocellular carcinoma, which seriously endangers human health. NASH pathogenesis is complex, and involves the interaction between hepatic parenchymal and non-parenchymal cells (NPCs), sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, and so on. Herein, the relevant research progress of NPCs in the pathogenesis of NASH is reviewed in order to further understand the role of NPCs in NASH.
